Light microscopy image of  bio-molecular architecture built in the group of Prof. M. Norton, Marshal University, WV.
 
 
 
The THz signature of artificial DNA nanocrystal.
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The high spectral resolution of Vibratess Spectrometer makes it possible to observe well resolved vibrational resonance modes (or groups of several modes at close frequences-vibrational bands) for biomolecules, as well as for cells. A unique spectral signatures are generated from vibrational resonances of DNAs, RNAs, proteins.
 
 Sub-THz Spectrometeris currently commercially available. All of our customers will be  provided with complete training package, as well as an initial database of sub-THz signatures for their molecules (or cells) of interest.
 
Development and building narrow sub-band  customized spectroscopic sensors for detecting specific molecular or cell biomarkers is possible as well.
Below we demonstrate the examples of the services that can be provided by Vibratess to generate THz signatures database from macromolecules of interest for customers.
For many years Vibratess has been working on developing procedures to predict sub-THz spectroscopic signatures from molecular components of biological molecules using molecular dynamics (MD) and other software packages and available information on molecular/atomic composition and three dimensional structures, such as protein data base (PDB) files.
THz signatures from nanogram sample of normal (green curve) and ovarian cancer (red) cells [Samples from UVA Medical School, Prof. A. Jazaeri and Prof. C. Moskaluk, measurements at Vibratess, LLC].
1. THz Spectroscopic characterization of biological and organic materials including biological macromolecules and microorganisms
 
2. Creating experimental database for THz spectroscopic signatures from specific biological materials and objects
 
3. Computational modeling for prediction and analysis of absorption signatures from biological molecules 
Comparison of experimental and simulated spectra of protein thioredoxin from E.coli.
 
Vibratess’ Services
A big artificial DNA nanocrystal. Scale bar 100 microns.
Sizov I., Rahman M., Gelmont B., Norton M. L., and Globus T., "Sub-THz spectroscopic characterization of vibrational modes in artificially designed DNA monocrystal", Chem. Phys., vol. 425, pp. 121–125, Nov. 2013. http://dx.doi.org/10.1016/j.chemphys.2013.08.015). 
Sub-THz absoprtion signature of  DNA from E.coli cells [T. Globus, I. Sizov, and B. Gelmont, “Teraherz vibrational spectroscopy of E. coli and molecular  constituents: Computational modeling and experiment,” Advances in Bioscience and Biotechnology, 2013, 4, 493-503, doi:10.4236/abb.2013.43A065]